نوع مقاله : مروری
نویسندگان
1 موسسه تحقیقات فنی و مهندسی کشاورزی
2 گروه علوم و صنایع غذایی، پردیس بینالمللی ارس، دانشگاه تهران، تهران، ایران
3 گروه پرستاری، دانشگاه علوم توانبخشی و سلامت اجتماعی، تهران، ایران
10.22092/fooder.2026.372378.1449
چکیده
نانوساختارهای الکتروریسیشده امکان ریزپوشانی ترکیبات طبیعی را در بستری با ابعاد نانومتری فراهم میکنند. این فرآیند با اعمال میدان الکتریکی به محلولی از پلیمر و حلال، منجر به تولید الیافی با سطح ویژۀ بالا و ساختار قابلکنترل میشود. شرایط فرآیند الکتروریسی از تخریب ترکیبات حساس جلوگیری میکند. پایداری ترکیبات طبیعی در الیاف به ویژگیهای محلول، پارامترهای الکتروریسی و نوع برهمکنش با ماتریس پلیمری وابسته است. یکی از کاربردهای اصلی این ساختارها، حفظ خواص ضدمیکروبی و آنتیاکسیدانی در محصولات غذایی است. در این حالت، ترکیبات طبیعی بهتدریج از ماتریس الیاف رها میشوند و ماندگاری مواد را افزایش میدهند. همین ویژگی در حوزۀ دارورسانی نیز استفاده میشود، جایی که تنظیم سینتیک رهایش، اثربخشی ترکیبات مؤثر را طی زمان حفظ میکند. ساختارهای ترکیبی از جمله هسته–پوسته، چندلایه، جهتیافته و بافته شده، امکان طراحی رفتارهای رهایشی متنوع را فراهم میآورند. در محیطهای زیستی، شباهت نانوالیاف به ماتریس خارج سلولی، تعامل سلولی را تسهیل میکند و حضور ترکیبات طبیعی میتواند القای رشد یا تمایز سلولی را هدایت کند. این ویژگی در بازسازی بافت و همچنین در فرمولاسیون محصولات موضعی برای پوست کاربرد دارد، جایی که نفوذ ترکیبات فعال و پایداری آنها همزمان بهبود مییابد. بر این اساس، هدف این مقالۀ مروری بررسی تحلیلی و مقایسهای پیشرفتهای اخیر در زمینۀ ریزپوشانی ترکیبات طبیعی با استفاده از نانوساختارهای الکتروریسیشده، با تمرکز بر چهار حوزه کاربردی کلیدی است: صنایع غذایی و بستهبندی فعال، دارورسانی و کاربردهای دارویی، مهندسی بافت و کاربردهای زیستپزشکی، و محصولات آرایشی و بهداشتی.
کلیدواژهها
موضوعات
عنوان مقاله [English]
Advances and Applications of Electrospun Nanostructure-Based Encapsulation of Natural Compounds
نویسندگان [English]
- Negar Roshani-Dehlaghi 2
- Ali Ekrami 3
1
2 Department of Food Science and Industry, Ares International Campus, University of Tehran, Tehran, Iran
3 Department of Nursing, University of Social Welfare and Rehabilitation Sciences, Tehran, Iran
چکیده [English]
Electrospun nanostructures ofer a nanoscale matrix for encapsulating natural compounds. This process uses an electric field applied to a polymer-solvent solution to produce fibers with high specific surface area and controllable morphology. Electrospinning conditions help prevent degradation of sensitive compounds. Thestability of natural compounds within fibers depends on solution properties, process parameters, and interactions with the polymer matrix. A primary application is preserving antimicrobial and antioxidant properties in food products, where compounds are gradually released from the fiber matrix to extend shelf life. Thesame controlled release principle is used in drug delivery systems, maintaining active agent efficacy over time. Composite structures such as core-shell, multilayer, aligned, and woven designs enable diverse release pr of iles. In biological environments, the nan of iber's resemblance to the extracellular matrix facilitates cell interactions, while incorporated natural compounds guide cell growth or differentiation. This supports tissue regeneration and topical skin formulations, enhancing both active compound penetration and stability. Accordingly, this review presents an analytical and comparative examination of recent advances in electrospun nanostructure-based encapsulation of natural compounds, focusing on four key application areas: the food industry and active packaging, drug delivery and pharmaceutical applications, tissue engineering and biomedical uses, and cosmetics and personal care products.
کلیدواژهها [English]
- Electrospinning
- Encapsulation
- Natural Compounds
- Nanofibers
- Controlled Release
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